オオタケサトウ マルセロ
  Marcello Otake Sato
   所属   新潟薬科大学  医療技術学部 臨床検査学科
   職種   教授
言語種別 英語
発行・発表の年月 2005/08
形態種別 論文
査読 査読あり
標題 Evaluation of clinical and serological data from Taenia solium cysticercosis patients in eastern Inner Mongolia Autonomous Region, China
執筆形態 共著
掲載誌名 Transactions of the Royal Society of Tropical Medicine and Hygiene
掲載区分国外
巻・号・頁 99(8),pp.625-630
著者・共著者 ◎Ikejima, T; Piao, ZX; Sako, Y; Sato, MO; Bao, S; Si, R; Yu, F; Zhang, CL; Nakao, M; Yamasaki, H; Nakaya, K; Kanazawa, T; Ito, A
概要 Neurocysticercosis (NCC) is one of the major causes of neurological disease in China. ELISA and immunoblotting using glycoproteins purified by preparative isoelectric focusing were used to detect human cysticercosis in Tongliao area, Inner Mongolia, China in 1998. Approximately 89% (39 of 44 inpatients and outpatients with suspected NCC at Tongliao City Hospital) were residents of Inner Mongolia. About 53% were male and 77% were of working age (18–59 years), and 32% were farmers. Immunoblotting and ELISA showed a high correlation. Of the 44 patients, 31 positive by cerebral computed tomography (CT) scan were confirmed serologically to have cysticercosis. In the ELISA, patients with no lesions by CT scan had lower OD values, similar to those of normal serum. These findings confirm that both ELISA and immunoblotting assays are sufficiently sensitive to detect asymptomatic or symptomatic cysticercosis patients.
DOI https://doi.org/10.1016/j.trstmh.2005.04.008
ISSN 0035-9203