オオタケサトウ　マルセロ   Marcello Otake Sato    所属   新潟薬科大学  医療技術学部 臨床検査学科    職種   教授
言語種別	英語
発行・発表の年月	2011/01
形態種別	論文
査読	査読あり
標題	A possible nuclear DNA marker to differentiate the two geographic genotypes of Taenia solium tapeworms
執筆形態	共著
掲載誌名	Parasitology International
掲載区分	国外
巻・号・頁	60(1),pp.108-110
担当区分	筆頭著者
著者・共著者	◎Sato, Marcello Otake; Sako, Yasuhito; Nakao, Minoru; Wandra, Toni; Nakaya, Kazuhiro; Yanagida, Tetsuya; Ito, Akira
概要	Cysticercosis caused by infection with embryonated eggs of the pork tapeworm Taenia solium is an important cause of neurological disease worldwide. Based on the phylogenetic analysis of mitochondrial DNA, the pathogen has been divided into two geographic clades, corresponding to Afro-American and Asian genotypes. In this study the genotyping of T. solium was carried out by using the nuclear DNA sequences of the immunodiagnostic antigen genes Ag1V1 and Ag2. The two geographic genotypes were supported by the Ag2 sequences, especially showing unique substitutions in each of the genotypes. It seems likely that the Ag2 may be a novel nuclear DNA marker to distinguish the two geographic genotypes of T. solium.
DOI	https://doi.org/10.1016/j.parint.2010.11.004
ISSN	1383-5769