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オオタケサトウ マルセロ
Marcello Otake Sato 所属 新潟薬科大学 医療技術学部 臨床検査学科 職種 教授 |
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| 言語種別 | 日本語 |
| 発行・発表の年月 | 2023/01 |
| 形態種別 | 論文 |
| 査読 | 査読あり |
| 標題 | Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for differential identification of adult Schistosoma worms. |
| 執筆形態 | 共著 |
| 掲載誌名 | Parasites & vectors |
| 掲載区分 | 国外 |
| 巻・号・頁 | 16(1),20頁 |
| 著者・共著者 | Jurena Christiane Ebersbach, Marcello Otake Sato, Matheus Pereira de Araújo, Megumi Sato, Sören L Becker, Issa Sy |
| 概要 | The aims of this study were to develop and validate a species-specific database for adult Schistosoma identification, and to evaluate the effects of different storage solutions (ethanol and RNAlater) on spectra profiles.58 new Schistosoma samples were analyzed, of which 100% (58/58) were correctly identified to genus level (log score values ≥ 1.7) and 81% (47/58) were reliably identified to species level (log score values ≥ 2). The spectra profiles showed some differences depending on the storage solution used. All the machine learning algorithms classified the samples correctly.CONCLUSIONS:MALDI-TOF MS can reliably distinguish adult S. mansoni from S. japonicum. |
| DOI | 10.1186/s13071-022-05604-0 |
| ISSN | 1756-3305 |
| PMID | 36658630 |