オオタケサトウ　マルセロ   Marcello Otake Sato    所属   新潟薬科大学  医療技術学部 臨床検査学科    職種   教授
言語種別	日本語
発行・発表の年月	2023/12
形態種別	論文
査読	査読あり
標題	Development and evaluation of an immunochromatography-based point-of-care test kit for a rapid diagnosis of human cysticercosis.
執筆形態	共著
掲載誌名	Food and waterborne parasitology
掲載区分	国外
巻・号・頁	33,e00211頁
著者・共著者	Lakkhana Sadaow, Patcharaporn Boonroumkaew, Rutchanee Rodpai, Penchom Janwan, Oranuch Sanpool, Tongjit Thanchomnang, Yasuyuki Morishima, Marcello Otake Sato, Yasuhito Sako, Kaoru Kobayashi, Misako Iwai, Wanchai Maleewong, Hiroshi Yamasaki, Pewpan M Intapan
概要	An immunochromatography-based test (ICT) kit, using T. solium cyst fluid as antigen, was manufactured to detect anti-T. solium IgG antibodies in human serum. To evaluate the kit, we used 187 serum samples including 24 from proven/confirmed cysticercosis cases, 133 from cases with other parasitosis and 30 healthy controls. Diagnostic efficiencies were calculated. The sensitivity, specificity, and accuracy were 83.3%, 92.0%, and 90.9%, respectively. Moreover, the ICT was positive before treatment but became negative after treatment, implying that this kit is also useful for follow-up monitoring post-treatment. In conclusion, we have successfully developed and present preliminary evaluation of an easy-to-handle rapid diagnostic tool for human cysticercosis in the form of an ICT platform using as antigen fluid from T. solium cysticerci.
DOI	10.1016/j.fawpar.2023.e00211
ISSN	2405-6766
PMID	37868190