イワタ　タケオ   Takeo IWATA   岩田　武男    所属   新潟薬科大学  薬学部 薬学科    職種   准教授
言語種別	英語
発行・発表の年月	1999/09
形態種別	論文
標題	Molecular cloning of newt sex pheromone precursor cDNAs: evidence for the existence of species-specific forms of pheromones.
執筆形態	共著
掲載誌名	FEBS letters
掲載区分	国外
巻・号・頁	457(3),pp.400-4
著者・共著者	Iwata T, Umezawa K, Toyoda F, Takahashi N, Matsukawa H, Yamamoto K, Miura S, Hayashi H, Kikuyama S
概要	Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates.
ISSN	0014-5793
PMID	10471817